Itching for a CSU Cure: An Older African American Adult Male With Widespread, Persistent Pruritus

Dermatology
Curriculum:
Itching for a CSU Cure: The Shift From Symptom Relief to Curative Therapies
Credits:
0.25 AMA PRA Category 1 Credit(s) 0.25 ANCC Contact Hours 0.25 ACPE
Launch Date:
December 16, 2021
Expiration Date:
December 16, 2022

Primary Audience:

Allergists, dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care/pharmacy directors.

Relevant Terms:

Dermatology; pruritus; lesions; nodules; quality of life; angioedema; hives; CSU; chronic urticaria; off-label agents; wheals; skin; skin of color; differential diagnosis; chronic spontaneous urticaria

Chesahna Kindred, MD, MBA, FAAD (Chair)

Assistant Professor of Dermatology
Howard University College of Medicine
Washington, DC
Kindred Hair & Skin Center
Columbia, MD

Dr Chesahna Kindred is a board-certified dermatologist, published research author, and national speaker. She was recently named “Physician of the Year” by the Daily Record. Dr Kindred grew up in South Central Los Angeles, an area of California known for its tough streets and strong community spirit, and a place where overcoming adversity was not simply a choice, but a way of life. It was this environment that planted the seed for Dr Kindred’s future in her field, cultivating a strong ambition and drive to serve her community, empowering people through beauty.

Growing up, she quickly garnered a reputation for her love of education and her desire to help others achieve their goals. It was this drive that led her to pursue a career within the field of dermatology. Dr Kindred began her studies at the University of Southern California where she received her Bachelor of Science with a minor in Spanish. She then relocated to Ohio where she continued to push herself in her educational pursuits, earning not just her MD degree, but also an MBA at the University of Cincinnati.

Dr Kindred was awarded a full scholarship as a Yates Fellow for the MBA program, where she was only the third person in the history of University of Cincinnati to receive the dual MD/MBA degree. She then took up her residency and fellowship at Howard University, an institution that pioneered Ethnic Dermatology. It was here that Dr Kindred gained her passion and focus on hair loss and ethnic skin.

Soon after graduating from her dermatology residency at Howard University, Dr Kindred became a leading dermatologist at MedStar Health in the Baltimore area. Five years later, she founded Kindred Hair & Skin Center in Columbia, Maryland, where she treats people of all ages and ethnicities.

Dr Kindred remains on the cutting edge of hair loss treatment, using 3 different methods of treating hair loss with growth factors, such as PRP, on a regular basis. Currently, she owns the first dermatology office with a full-service salon that specializes in hair loss, PeterKINdred Hair & Scalp Wellness Center. The stylist in the salon is Susan Peterkin, co-founder of the Natural Hair Industry Convention.

Locally, Dr Kindred is heavily involved in community service, often organizing health fairs, mentoring aspiring doctors, and working with local churches and community organizations to help educate and empower the community at large.

Within the field of dermatology, Dr Kindred is:

  • Founder and President, Onyx Medical Society, a society of the National Medical Association
  • Chair of the National Medical Association, Dermatology Section
  • Fellow of the American Academy of Dermatology (FAAD)
  • Member of the Women’s Dermatological Society, American Society of Dermatologic Surgery, Maryland Dermatologic Society, and Monumental Dermatology Society

Outside of dermatology, Dr Kindred is:

  • Leader of the African American Community Roundtable, Health Committee
  • Leader of Celebration Church Health & Wellness Ministry
  • Deacon at Celebration Church at Columbia

Dr Kindred has been featured on:

  • Disney’s Doc McStuffins
  • WMAR Baltimore ABC News
  • WJZ Baltimore CBS News
  • WBFF Baltimore Fox News
  • Dermatology Times

Dr Kindred has several publications concerning an array of dermatologic topics including co-writing chapters in leading dermatology textbooks. Her publications include but are not limited to hair loss, skin cancer, and treatments in patients with skin of color. Philosophically her focus of “Empowering through beauty” has resonated with patients worldwide. Understanding the desire people have to feel as beautiful outside as they do within, Dr Kindred helps them achieve the balance that allows people to feel complete. True beauty is not about vanity, but instead about empowering one’s self to have the confidence to live life to the fullest.

Jonathan A. Bernstein, MD 

Professor of Clinical Medicine
University of Cincinnati Medical Center
Partner, Bernstein Allergy Group and Clinical Research Center
Cincinnati, OH

Dr Jonathan A. Bernstein is Professor of Clinical Medicine in the Department of Internal Medicine, Division of Immunology/Allergy Section at the University of Cincinnati Medical Center and partner of the Bernstein Allergy Group and Clinical Research Center. He received his MD from the University of Cincinnati College of Medicine in 1985 and completed his residency training in Internal Medicine at the Cleveland Clinic Hospital from 1985-1988 and his Allergy/Clinical Immunology training at Northwestern University in Evanston, Illinois, from 1988-1990.

Dr Bernstein’s research interests are related to environmental impact on asthma, chronic urticaria, angioedema, food and drug allergies, chronic rhinitis subtypes, chronic cough, and progesterone and seminal plasma hypersensitivity. He is currently Secretary-Treasurer of the American Academy of Allergy, Asthma & Immunology (AAAAI) and a member of the AAAAI Foundation council. He will be President of the AAAAI in 2023 and Chair of the Foundation in 2024. Dr Bernstein also sits on the World Allergy Organization (WAO) board of directors and is on the medical advisory board of the Hereditary Angioedema Association (HAEA). He was the recipient of the 2019 AAAAI Distinguished Clinician Award and the 2019 WAO Outstanding Clinician Award. Dr Bernstein is the author of over 360 peer-reviewed articles in addition to numerous book chapters, and is the editor of 5 books pertaining to asthma, rhinitis, and immunodeficiency. 

1. Discuss diagnostic criteria for chronic spontaneous urticaria (CSU) and how the condition presents differently in patients of color
2. Compare the efficacy and safety trial data of therapies for CSU that are in late-stage clinical development
3. Apply shared decision-making to help patients and caregivers identify the risks and benefits of each CSU therapy

SPONSORSHIP & SUPPORT
This educational activity is jointly provided by Global Education Group and Spire Learning.

This activity is supported by educational grants from Sanofi Genzyme and Regeneron Pharmaceuticals.


PROGRAM OVERVIEW
Chronic spontaneous urticaria (CSU) is a chronic immune-mediated condition characterized by sudden development of wheals and/or angioedema, as well as presenting with significant debilitation and considerable burden on patients’ quality of life. The diagnosis and management of CSU is complex, and despite currently available treatment options, many patients with CSU remain inadequately controlled. As a result, many health care professionals may miss opportunities to deliver evidence-based care utilizing safe and effective, targeted therapies. Join our expert faculty as they discuss patient scenarios to highlight methods to avoid missed opportunities for the care team, develop curative (as opposed to prophylactic symptom control) strategies, and ultimately provide optimal care for patients with CSU.

TARGET AUDIENCE
The target audience will be comprised of allergists, dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care/pharmacy directors.

LEARNING OBJECTIVES
Upon completion of this educational activity, learners should be better able to:

  • DISCUSS diagnostic criteria for chronic spontaneous urticaria (CSU) and how the condition presents differently in patients of color
  • COMPARE the efficacy and safety trial data of therapies for CSU that are in late-stage clinical development
  • APPLY shared decision-making to help patients and caregivers identify the risks and benefits of each CSU therapy

ACCREDITATION AND CREDIT DESIGNATION
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Spire Learning. Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Spire Learning, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation
Global Education Group designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

This educational activity for 0.25 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacist Accreditation Statement
Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.


Credit Designation Statement
Global Education Group designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-21-154-H01-P) This is a knowledge-based activity.

HOW TO RECEIVE CREDIT
There is no fee for this educational activity. To receive credit for your participation in this educational activity:

  • Read the objectives and other introductory CME information
  • Complete the preassessment prior to the start of the activity
  • Participate in the chronic urticaria case activity
  • Complete the postassessment and evaluation at the conclusion of the activity

If you are seeking credit, you must complete the evaluation at the conclusion of the activity.

For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.

CONFLICTS OF INTEREST STATEMENT
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias. 

All relevant financial relationships have been mitigated.

PLANNING COMMITTEE
Chesahna Kindred, MD, MBA, FAAD (Chair)
Assistant Professor of Dermatology
Howard University College of Medicine
Washington, DC
Kindred Hair & Skin Center
Columbia, MD

Disclosures:
Consulting Fees (eg, Advisory Board): Aerolase; Eli Lilly and Company; Sun Pharmaceuticals; UCB, Inc
Speakers’ Bureau: Aerolase; Eli Lilly and Company; Novartis Pharmaceuticals Corporation; Nutrafol; Sun Pharmaceuticals; UCB, Inc  

Jonathan A. Bernstein, MD 
Professor of Clinical Medicine
University of Cincinnati Medical Center
Partner, Bernstein Allergy Group and Clinical Research Center
Cincinnati, OH

Disclosures:
Consulting Fees (eg, Advisory Board): Allakos Inc; AstraZeneca; BioCryst Pharmaceuticals, Inc; BioMarin Pharmaceutical Inc; Blueprint Medicines; Celldex Therapeutics; CSL Behring; Genentech, Inc; Ionis Pharmaceuticals, Inc; Merck & Co, Inc; Novartis Pharmaceuticals Corporation; Pharming; Pharvaris; Sanofi Regeneron; Takeda Shire
Contracted Research: Allakos Inc; AstraZeneca; BioCryst Pharmaceuticals, Inc; BioMarin Pharmaceutical Inc; Blueprint Medicines; Celldex Therapeutics; CSL Behring; Genentech, Inc; Ionis Pharmaceuticals, Inc; Merck & Co, Inc; Novartis Pharmaceuticals Corporation; Pharming; Pharvaris; Sanofi Regeneron; Takeda Shire
Honoraria: AstraZeneca; BioCryst Pharmaceuticals, Inc; CSL Behring; Genentech, Inc; Merck & Co, Inc; Novartis Pharmaceuticals Corporation; Pharming; Sanofi Regeneron; Takeda Shire
Speakers’ Bureau: AstraZeneca; BioCryst Pharmaceuticals, Inc; CSL Behring; Genentech Inc; Merck & Co, Inc; Novartis Pharmaceuticals Corporation; Pharming; Sanofi Regeneron; Takeda Shire

EDUCATIONAL PLANNING COMMITTEE
Global Education Group
Rhys Williams, MSN, FNP-C, RN; Lindsay Borvansky; Andrea Funk; Liddy Knight; Ashley Cann; Kim Rodriguez: No relevant financial relationships with any commercial interests.

Spire Learning
Mairead Early, Christopher Washburn, PhD, and Kimberly Miniter have nothing to disclose.

Reviewer
Lindsay Borvansky: No relevant financial relationships with any commercial interests.

OFF-LABEL STATEMENT
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Spire Learning do not recommend the use of any agent outside of the labeled indications. 

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

PRIVACY POLICY:
Spire Learning Privacy Policy:
Spire Learning, LLC, is committed to protecting the privacy of personal information from our participants and educational collaborators. Spire maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of personal information.
 
Collection and Use of Your Personal Information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected and retained, and used by Spire Learning, LLC, to continuously improve the learning experience.
 
Spire Learning, LLC, will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Spire will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws. 

COPYRIGHT INFORMATION:
Copyright © 2022 by Spire Learning, LLC and Global Education Group. All rights reserved including translation into other languages. No part of this publication or activity may be reproduced or transmitted in any form, by any means, without prior written permission of Spire Learning, LLC.

COURSE VIEWING REQUIREMENTS

Supported Browsers:
Microsoft Edge
Google Chrome 60 or higher
Mozilla Firefox 60 or higher
Apple Safari 11.0 or higher
For video, install the latest version of Quicktime.
Supported Phones & Tablets:
iOS 9.3 and higher
Android 7.0 (Nougat or higher)
Microsoft Windows 8
Chrome OS

 
Additional Recommendations and Requirements
Display Resolution & Color Depth Resolution
- 960 X 768 minimum
- 1024 X 768 recommended min.

Color Depth
- 8 bits (256 colors) minimum
- 16 bits (High colors) minimum
Audio - Microphone
- Speakers or headphones
- Audio recording support
Word Processing Software that can open, modify, and save documents in Rich Text Format (RTF). Microsoft Word and PowerPoint are recommended.

Contact
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.